[CRS_META] declined: crsociety - topicality/trim

[Tim C.]

This message was forwarded to Conrad off-list.
-Tim C.

>> ----- Original Message ----- 
>> From: "andy"
>> To: "The CR Society Main Discussion List" <cr at lists.calorierestriction.org>
>>
>
>> dear conrad
>>
>> may i inquire as to what suntan lotion you have found most effective?
>>
>> thanks
>>
>> andy
>>
>>
>> ----- Original Message ----- 
>> From: "CONRAD ROLAND" <coro at hawaii.rr.com>
>
> Hi Andy,
>
> I forwarded this message off-list to Conrad.
>
> -Tim C.
>

**the rest of the original is below**

To: "The CR Society Main Discussion List" <cr at lists.calorierestriction.org>
Sent: Saturday, May 12, 2007 10:55 AM
Subject: Re: [CR] Resveratrol - skin

>
> On 5/11/07 10:32 AM, "Christopher Dowling" <christopher.a.dowling at gmail.com>
> wrote:
>> WRT your BCC, Conrad, was it biopsied, or just clinically
>> diagnosed?  I assume you acquired it before you began
>> taking high levels of resveratrol?  How long did it take to
>> resolve after you started taking high dose resveratrol?
>> What is left of the tumor- normal skin, or scar?
>
> Yes, I aquired BCC before taking high levels of resveratrol.
>>
> Nothing to worry. I never had a serious case of basal cell carcinoma
> (BCC). I developed a small, max. 5 mm lesion between the nose and the
> eyelid. It was removed by excision in 2000, biopsied and confirmed BCC. The
> same spot returned after a few months, was excised again, and it's quiet
> since. No visible scar, my local surgeon did a great job, probably much
> better than a dermatologist.
>
> At that time I had several small (2-3 mm pre-cancerous) lesions on head,
> shoulders, arms and trunk. They were removed with cryotherapy (liquid
> nitrogen) and I started to use resveratrol as an experimental treatment and
> preventative AFTER the BCC had developed. I was quite successful with
> prevention through topical and oral resveratrol, but old "spots" would not
> respond  or re-surface after a few weeks. I also tried several other
> polyphenols - long story - and various oils.
>
> I am a firm believer of *moderate* sun exposure for reasons of vitamin D
> production, general health and well-being, and I really like a good suntan.
> With my special protective oil/lotion and high-dose oral supplementation I
> could spend at least 30-60 minutes in the tropical sun without wearing a
> shirt. There is recent literature on the benefits of sun exposure and
> suntans beyond vitamin D. Melanin is by far the best sun protection!
>
> The literature on resveratrol and other polyphenols (green and black tea
> catechins, pomegranate/ellagic acid, curcumin, genistein...) used for the
> prevention of non-melanoma skin cancer is quite impressive and practical
> applications in supplement form and topical oils or lotions are already
> available or in the pipeline. Most of them are too weak, so far, to have any
> effects.
>
> Finally, since I have been taking high doses of resveratrol *and* many other
> phytochemicals in food and supplements, since fall of 2005, and since I had
> started on CR sixteen months ago, the remaining traces of skin cancer have
> almost completely disappeared, my skin has cleared up - it was apoptosis in
> action and clearly visible, day after day could I remove dead cells from
> old, raised, pre-cancerous spots . This process took about one year.
> The skin can be viewed as a very honest indicator of general good health.
> Some of the same promoters of cancer in various organs can also be found in
> the epidermis and below, for instance survivin, a transcription factor,
> which inhibits apoptosis and promotes proliferation of cancer cells.
>
> It is perhaps no coincidence that my recent lab result for IGF-1
> [Insulin-like Growth Factor 1] is very low at 62.6 ng/mL (reference values
> 64-188). I leave it up to Dr. Luigi Fontana and others to make a
> professional judgement about my low IGF-1. It seems to be the result of
> significant CR plus ON plus OS - very low body fat, low BMI, and very low
> HbA1c.
>
> Sorry, short question - long answer, but (suntanned) skin is one of my
> passions.
> My BCC skin cancer goes probably all the way back to early, excessive sun
> exposure in my teen years (some horrible sunburns), during my first years in
> Hawaii, and may have been, finally,  triggered by a strong photosensitizing
> supplement that I took in 2000: St. John's Wort (Hypericum). I never touched
> it again.
>
> Enjoy the sun "in moderation", like red wine and dark chocolate and many
> other polyphenolic delights, and don't be afraid of a nice suntan that needs
> to be built up slowly over weeks in light-skinned people. Dark skin - no or
> hardly any BCC problems at all.
>
> Conrad Roland
> coro at hawaii.rr.com
> (below 4.0%)
>
>
>
>
>>
>> On 5/11/07, CONRAD ROLAND <coro at hawaii.rr.com> wrote:
>>>  ...
>>> Less direct application via oral resveratrol and through the blood stream
>>> seems to be OK and my BCC has largely disappeared through combined effects
>>> of various phytochemicals and ...... CR + ON !
>
>
>
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